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Despite reasons to believe that GLP-1RA maintains similar glycemic regulation capabilities in patients of different body weights, 140 its comprehensive metabolic capability and resulting hepatic outcomes have not been thoroughly evaluated

Genetic screening is advisable before initiation in at-risk populations

Patients often weigh how they feel on treatment, how easy it fits into routine care, and how much it costs

This is especially true when we consider the titration schedule and side effects associated with starting GLP-1s, and the weight regain that can happen when the medications are stopped

The uncontrolled use of antibiotics in agriculture and inappropriate therapeutic practices has provided an evolutionary advantage to bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), and others that have become resistant to one or multiple types of antibiotics, contributing to the dramatic situation in healthcare (Figure 2)

Novo Nordisks Wegovy pill is still outselling Lillys Zepbound at a comparable launch stage by roughly 1.5x