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Different mechanisms may contribute to these effects

In addition to the final key morphological changes, the increase of free iron and lipid peroxidation are also important features of ferroptosis, and it is also related to the instability of the plasma membrane, disrupted protein stability, and cytoskeleton rearrangement, leading to the obvious balloon phenotype of the cells (Louandre et al., 2013

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Its reputation in the recovery space is built on this local, site-directed profile

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Notably, the body weight of the free Dox group decreased compared to other groups, indicating that L P B-3 vesicles might reduce the side effects of free drugs