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Hancock, R
The STEP-1 trial (N=1,961) showed semaglutide 2.4 mg produced 14.9% mean body weight loss at 68 weeks versus 2.4% with placebo [1]
Never use medication past this date, regardless of how much remains
Therefore, Mounjaro is expected to have higher efficacy than conventional GLP-1 receptor agonists
Neurology 57:15151517 Coles LD, Tuite PJ, Oz G, Mishra UR, Kartha RV, Sullivan KM, Cloyd JC, Terpstra M (2018) Repeated-dose oral N-acetylcysteine in Parkinson's disease: pharmacokinetics and effect on brain glutathione and oxidative stress
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