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GLP1/E improves metabolic and gonadal traits in a PCOS model of ovarian dysfunction We next assessed the metabolic, gonadal, and hormonal effects of the intervention with equivalent doses (10 nmol/kg) of GLP1, E, or GLP1/E in PNA mice, which retain ovulatory capacity albeit with clear dysregulation of ovarian cyclicity
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In Phase 2 clinical trials, the average duration of diarrhea episodes for Retatrutide users was just 1-3 weeks
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