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GLP-1RAs have been shown to exert beneficial effects on the maintenance of endothelial integrity

But it is not the only outcome, and in patients with established atherosclerotic disease or heart failure, it may not even be the primary mechanism of benefit

Treatment of mice with NAC NAC (Sigma, A8199) was made fresh for each experiment in 0.9% saline at 20 or 30 mg/ml

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By contrast, in an updated meta-analysis of 86 published studies of the association of the polymorphism with CHD, the excess CHD risk in TT homozygotes compared to CC homozygotes was 15%