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1.4 Regulatory Status and Approved Indications Semaglutide-based therapies are approved in multiple jurisdictions for: Type 2 diabetes mellitus management Chronic weight management in obese or overweight individuals Cardiovascular risk reduction in select populations Approval frameworks emphasize both glycemic endpoints and broader cardiometabolic outcomes
2007, 21 (Suppl 1): 13-23
From the perspective of precision medicines, combinatorial agonism might be precisely designed to reflect pharmacological profiles of individual receptors such that diabetic patients at different disease stages could be prescribed with different multi-targeting agonists to take personalized therapeutic advantages
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