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Maretty L, Gill D, Simonsen L, Soh K, Zagkos L, Galanakis M, Sibbesen J, Iglesias MT, Secher A, Valkenborg D, Purnell JQ, Knudsen LB, Tahrani AA, Geybels M (2025) Proteomic changes upon treatment with semaglutide in individuals with obesity

A Phase 2 trial published in JCEM demonstrated sustained GH elevation (mean 60% increase) and IGF-1 increases of 4090% maintained across 12 months of daily dosing

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