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EClinicalMedicine 70, 102507
For superoxide anion, the main ROS, a first line of defense is represented by the enzyme superoxide dismutase, localized in the mitochondrial matrix
However, not every patient sees dramatic change
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- Gentle cleanse with a hydrating cleanser - Hydrating mist/toner - 12% Niacinamide serum (optional first) - Wait 510 min - Tretinoin cream - Cleanse - Niacinamide serum - Niacinamide moisturizer - Skipping sunscreen: Tretinoin increases UV sensitivity