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Conflicting evidence links chronic levodopa therapy in patients with Parkinson disease to an increased risk of symptomatic vitamin B12 deficiency, perhaps because carbidopa metabolism through the catechol-O-methyl transferase pathway may deplete vitamin B12-dependent cofactors (204
Injection site redness and itching can signal that degradation products are triggering a local inflammatory response
, Ross University 20+ years of clinical experience Frequently Asked Questions about B12 Injections This information was reviewed by Dr
Low B12 is clinically associated with low mood, anxiety, and emotional flatness
PMID 18245139
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