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Take-home message: - Peptides and assorted experimental drugs, like TB-500 and MK-677, are being recommended by fitness influencers to grow bigger muscles, lose fat, and recover from injuries faster - These drugs, many of which are claimed to boost levels of growth hormone, were studied in rodents and very small groups of human volunteers before being abandoned for not being beneficial or for causing unacceptable side effects - They are banned by the World Anti-Doping Agency and appear to be illegal in Canada and the United States, but can be purchased online

Evidence from animal and human studies demonstrates that GLP-1 RAs improve mitochondrial function, reduce oxidative stress, attenuate chronic inflammation, and enhance autophagic activity

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BOGOT, Colombia Most dermatologists and rheumatologists agree that GLP-1 receptor agonists (GLP-1 RAs), such as liraglutide, semaglutide, and tirzepatide, powerful antidiabetes and weight-loss drugs, have the potential to help some patients with psoriasis and psoriatic arthritis (PsA)