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Finally, a head-to-head comparison of tirzepatide and semaglutide was implemented with a follow-up of 52 weeks
doi:10.1073/pnas.1000645107 168
The GIP receptor activation adds complementary effects including enhanced insulin sensitivity, improved glucose disposal, and additional appetite regulation through central nervous system pathways
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The appetite suppression timeline on semaglutide means there may be a gap in coverage during the switch
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