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In this study, with a median follow-up of 25 months, the primary composite end point including cardiovascular death, MI, stroke, and hospitalization for unstable angina occurred in 406 patients (13.4%) in the lixisenatide group and in 399 (13.2%) in the placebo group (HR, 1.02

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doi: 10.3389/fendo.2021.645563

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Visible changes in body composition and clothing fit are common by this point