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inject slowly and steadily [11]

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In major trials assessing weight following cessation, namely STEP 1 6 , STEP 4 10 and SURMOUNT-4 11 , we noted that weight regain resembled an exponential recovery curve approaching an asymptote

The follow up period used to examine outcomes irrespective of ongoing use of the medication (emulating a modified intention-to-treat analysis of a clinical trial), started from the index date, and continued until study end (October 30, 2021), death, or initiation of a GLP1-RA in the DPP4i group, whichever came first (Fig

This will force other GLP-1 originators, such as tirzepatide and mazdutide, to reevaluate their pricing and market entry strategies and compel pipeline developers to recalibrate their China launch plans accordingly

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