The practical takeaway: AOD-9604 has a clean safety profile in trials but a failed Phase 2b efficacy endpoint
J Orthop Res 24:982989 Liu C, Aschbacher-Smith L, Barthelery N, Dyment N, Butler D, Wylie C (2011) What we should know before using tissue engineering techniques to repair injured tendons: a developmental biology perspective
Furthermore, all experiments were carried out under a blind protocol, and the effects were assessed by examiners who were completely unaware of the protocol
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Catalase activity in skeletal muscle of varying fiber types