Chemotherapy, immunosuppression, and anesthesia
Since most chemotherapeutic agents increase intracellular ROS levels [47], TIC resistance may stem from their high antioxidant content, including glutathione
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A study in the American Journal of Clinical Nutrition found that vitamin B12 in mothers is linked to better health in babies
These are controlled research readouts, and they describe model systems only, not clinical wound care in humans
Studies have shown that APC transporter proteins play a role in protecting tumor cells by actively transporting intracellular toxic substances or drugs to the extracellular compartment, thereby contributing to chemoresistance (70,71)