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In obese diabetic mice, oral elenolic acid produced a 10.7% reduction in body weight after four to five weeks, with blood glucose improvements comparable to liraglutide (Liu et al., 2024)

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doi: 10.31662/jmaj.2020-0021

Chronic stress elevates cortisol, which drives appetite, promotes abdominal fat storage, and can blunt the appetite-suppressing effects of GLP-1 medications

I think that we very soon will, and so I would encourage people to wait a little bit longer as the results of those trials are published in the next six months to a year and that prescribers who might writing the prescriptions for these medications will see those data and will be able to make informed choices about for whom these medications should be prescribed for alcohol or substance-use disorders

Sun protection: Always wear sunscreen during the day, as UV exposure can worsen hyperpigmentation