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To mimic the experimental Si/Al ratio of ~15 for CHA zeolite used in this work, four Si atoms on the CHA framework were replaced by 4 Al atoms, and compensating the charges with additional four H atoms on the O atoms, resulting in the model CHA zeolite of H 4 Al 4 Si 68 O 144 with the Si/Al of 17 42,44,69,70

However, this becomes dysfunctional in AD, further worsening the effects of oxidative stress (Dringen and Arend, 2025)

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Most of the published evidence on BPC-157 comes from animal and laboratory studies, with human clinical investigation still limited