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The standard dose is 2mg daily, with some protocols using 1-1.5mg for smaller individuals or those experiencing side effects

Solomon SD, Skali H, Anavekar NS, Bourgoun M, Barvik S, Ghali JK, et al

Along this line, it has been hypothesized that decreased levels of GSH, which have been detected in post-mortem brains of parkinsonian patients at the cellular level, are likely to affect mitochondrial functions via loss of mitochondrial GSH

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Everitt, J

This phenomenon might be responsible for TMAO promoting atherosclerosis through alternative pathways such as activating macrophages and endothelial cells or potentiating platelet aggregation