Always start low and listen to your body
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Orforglipron, an oral small-molecule GLP-1 receptor agonist, for the treatment of obesity in people with type 2 diabetes (ATTAIN-2): A phase 3, double-blind, randomised, multicentre, placebo-controlled trial
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Second, if you're weighing compounded versus brand-name, the regulatory trajectory is part of that math, because an FDA-approved brand-name product isn't subject to the same compounding uncertainty