Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunction
Managing a vitamin B12 deficiency during pregnancy may involve dietary changes, supplementation and, in some cases, B12 injections
One in three participants lost 20% or more of their starting weight
Mood changes can occur in individual users, but they appear rare and may reflect weight loss effects, nutritional deficiency, or pre-existing vulnerability rather than the drug itself
et al., Nature Medicine (Vol 30, 2024, pp 20372048)
Full reports of some of these trials have not yet been published