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All experiments were conducted with adherence to the National Institutes of Health Guide for the Care and Use of Laboratory Animals
in vitro (
Inhibition of cellcell spread nAbs are generally considered in the context of inhibiting infection of target cells by free virus particles in vitro but they can also inhibit the cellcell spread of a virus
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This study revealed some lysine acetylation (AcK) sites being accessible to SIRT1-catalysed deacetylation, i.e., AcK94, AcK98, AcK103, AcK237 and AcK289, and some sites identified by mass spectrometry (MS) resist deacetylation by SIRT1, i.e., AcK157, AcK172, AcK223 and AcK231, not excluding the possibility other deacetylases being capable to catalyse their deacetylation (Supplementary Fig
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