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Food and Drug Administration for the treatment of hepatic encephalopathy Efficacy and limitations of traditional agents in management of HE Lactulose and lactitol Lactulose (beta-galactosidofructose) and lactitol (beta-galactosidosorbitol) are synthetic nonabsorbable disaccharides (NADs) that are given orally or rectally in patients with HE, in order to trap ammonia in the gut, thereby limiting intestinal absorption
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