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This table makes the distinction crystal clear

No hepatic safety signal was observed

Targeted delivery of probiotics and their metabolites, based on the pathological link between intestinal microbiota metabolites and ferroptosis, may help inhibit ferroptosis, correct microbiota dysregulation, and restore immune homeostasis, offering a promising precision intervention strategy to alleviate IBD inflammation

J Leukoc Biol 62:5459 Wang J, Chen Y, Gao N, Wang Y, Tian Y, Wu J, Zhang J, Zhu J, Fan D, An J (2013) Inhibitory effect of glutathione on oxidative liver injury induced by dengue virus serotype 2 infections in mice

Or a BMI of 27 or above classified as overweight combined with at least one weight-related comorbidity

Non-responders exist even among ideal candidates