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doi:10.1136/bmj.i2231

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A GST of the zeta class (GSTZ1-1) is involved in the metabolism of dichloroacetate 83,84

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Further mechanistic studies have found that treatment with TMZ promoted cardiac Nrf2 expression, indicating that TMZ enhanced the clearance of oxidative stress by activating the GSH system through the Nrf2 signaling pathway [210]