With less internal volume, ligaments no longer hold skin taut and folds appear around the nose and mouth
Souza M, Al-Sharif L, Antunes VLJ, Huang DQ, Loomba R
Regarding pharmacotherapy, Dutch standards recommend a stepwise introduction of treatments based on glycated haemoglobin (HbA1c), starting with metformin then sequentially adding sulphonylureas, followed by the addition of insulin or glucagon-like peptide-1 receptor agonists (GLP-1RAs) or dipeptidyl peptidase-4 (DPP-4) inhibitors as required to achieve and maintain glycaemic targets [9]
Early results, like reduced appetite, can be seen within the first two months
These medicines help with weight management by slowing down the rate at which food leaves the stomach, a process called delayed gastric emptying
Wegovy is a chronic prescription medication that is designed to be taken on a long-term basis, as prescribed (which, in this case, is weekly)