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Other symptoms of more severe deficiency include seizures, trouble coordinating movement, and metabolic acidosis, which is a buildup of acid in the body and includes symptoms such as nausea and vomiting (NIH, n.d.)

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191 The mechanism of GLP-1 RA to improve dopaminergic degeneration and pathological -synuclein aggregation in the PD model may involve inhibiting the PI3K/Akt/mTOR pathway 192 and enhancing AMPK/PGC-1a signaling pathway

NIS Elements (v5.21.00) was used for cell confocal laser scanning microscopy imaging