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Lv et al., 2021)

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Rosemary [29], curcumin [30], milk thistle [31,32], mustard seed [33], and ginkgo biloba [34] increase glutathione levels in animal studies

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Furthermore, they noted that the mean inflammatory lesion count dropped from 5.1 at baseline to 2.8 (week 4) and 1.9 at week 8 for a total reduction of 63%

It is worth mentioning that ebselen does not contribute to the bioavailable selenium pool required for the biosynthesis of selenoproteins including seleno-GPxs and therefore its ability to detoxify hydroperoxides under cellular conditions can exclusively be attributed to GPx mimicking activity [77, 79]