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Notably, RSL3 is widely used as a pharmacological inhibitor of GPX4, although studies in cell-free systems suggest that it may also exhibit inhibitory activity toward thioredoxin reductase 1 (TXNRD1), a key NADPH-dependent antioxidant enzyme that maintains thioredoxin-mediated redox homeostasis

Both the innate and innate-like cells express GLP-1R

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This is due to cost, side effects, unrealistic expectations, and the challenge of weekly injections

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