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Patent protections for semaglutide the active ingredient in Ozempic and Wegovy are already lapsing in several major markets in 2026, and a tentative FDA approval for a generic injectable version was granted to Apotex and Orbicular earlier this year

Many patients experience improvement as their bodies adapt to the medication, though this adaptation may take longer than 8 weeks, particularly during Wegovy's 16-week titration period

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