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The first formal human safety test appeared in early 2025: two healthy adults given intravenous infusions, no control group, measuring only whether their organ markers moved

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Considering this, the elevated concentrations of these metabolites (sedoheptulose, mannoheptulose and 1.3-diaminopropane) are likely due to reduced growth and nucleotide synthesis due to nutrient deprivation, and a redirection of this pathway towards energy generation and preventing oxidative stress

doi: 10.1038/ni.2512 39 DinanTGBorreYECryanJF

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Published clinical data show: After a single injection, mean plasma GH concentrations increased 2 to 10-fold for 6 days or more