Investigational and Emerging Indications: MASH, Neuropsychiatric Signals, Seizure Modulation, Cravings, Fertility/PCOS, Pulmonary Outcomes MASH (metabolic-associated steatohepatitis): GLP-1 RAs decrease hepatic fat
Batrakoulis A et al
Head-to-head comparative trials examining inflammatory outcomes as primary endpoints are limited, and most evidence comes from individual studies or post-hoc analyses of cardiovascular outcome trials
For patients seeking GLP-1s, this difference can be important, Ramachandran said
Preclinical Synergy Data The one direct combination study comes from an animal trial
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