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Current state availability

For women with BMI over 30 (obesity), gain 11 to 20 pounds

Topiramate treatment protects bloodbrain barrier pericytes from hyperglycemia-induced oxidative damage in diabetic mice

Women using oral contraceptives should use an additional non-oral contraceptive method for 4 weeks after tirzepatide initiation and for 4 weeks after each dose escalation, as tirzepatide may reduce the effectiveness of oral contraceptives

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This pattern continues until you reach your maintenance dose, where most patients experience minimal to no nausea within 6 to 12 weeks