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-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO

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Natalie Hernandez is a pediatric endocrinologist with advanced fellowship training in pediatric obesity medicine, metabolism, diabetes, and hormone health

Gclc f/f mice were generated as described 30 and crossed with the Rosa26-CreERT2 mouse strain (Jackson Labs, #008463) or Nrf2 f/f mouse strain (Jackson Labs, #025433)

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Because overall food intake drops significantly, the quality of food choices becomes especially important. She recommends eating smaller meals that contain 20 to 30 grams (g) of protein and gradually increasing fiber intake, while minimizing greasy or very high-fat foods