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For instance, the downregulation of GPx4 has been correlated with the manifestation of radiation injury in various tissues including the intestine, hemopoietic system, lung, cardiovascular system, ovary, and skin of the murine model though enhancing the ferroptosis mode of cell death [67]
MAPK interacts with occludin and mediates EGF-induced prevention of tight junction disruption by hydrogen peroxide
However, research is not considered conclusive
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Conjugated PUFAs exhibit anti-cancer activity and promote expression of ferroptotic markers in vivo Finally, we assessed the anti-cancer activity of tung oil in an aggressive TNBC orthotopic xenograft model
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