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It is studied for potential roles in tissue repair, inflammation regulation, and gastrointestinal protection, but remains an investigational compound without approved medical use

Others split the weekly dose into two injections to reduce injection volume and potentially improve absorption consistency

Pralatrexate: 1 (milligram) mg of vitamin B12 as an injection no more than 10 weeks prior to the first dose and every 8 to 100 weeks thereafter