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Molecules 25, 2198

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Given the coupling between copper and energy status (e.g copper is a cofactor at Complex IV of the ETC) and how intensely metabolically active neurons are, it seems like short-term IP GHK-cu in the brain is acting analogously to the copper ionophore elesclomol in Tregs

administration to healthy volunteers [32]

Curr Protoc Cell Biol 2014