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GHK-Cu (Copper) is a small tripeptide found in plasma and reportedly releases at the time of injury

For a full breakdown of how AOD 9604 works, check out our companion article

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Additionally, histological examination confirmed the potent anti-inflammatory actions of compound 33

In vivo study demonstrated that topical application of OPs on the skin significantly alleviated moisture loss, epidermal hyperplasia, as well as degradation of collagen and elastin fibers caused by chronic UVB irradiation

For many people, the most effective long-term strategy isn't choosing between these approaches but building a routine that includes both - using retinol for its proven resurfacing and gene-activation benefits, and GHK-Cu for the deeper repair work that retinol doesn't cover