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Animal care and welfare were performed in accordance with the Guide for the Care and Use of Laboratory Animals
Rapid correction of deficiency is required
Preclinical studies in rodents have demonstrated reductions in fat mass, improved insulin sensitivity, and increased metabolic rate without significant changes to food intake (Neelakantan et al., 2019)
TB-500 contributes systemic anti-inflammatory effects that may benefit inflammatory bowel conditions, though its primary value lies in tissue applications beyond the gut
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