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19 The dual GIP/GLP-1 RA tirzepatide has demonstrated a similar but sometimes more pronounced GI profile compared with semaglutide in clinical-development programs

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SGLT-2 inhibitors: Ketone education, sick-day rules, hydration, and clear stop rules are the non-negotiable foundation for safe use

This means that your body composition your physiquewill be different, even if you ultimately end up at the same total weight

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This is because the liver partly overlies the stomach and obesity can cause it to become enlarged