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DeNicola GM, Karreth FA, Humpton TJ, Gopinathan A, Wei C, Frese K, Mangal D, Yu KH, Yeo CJ, Calhoun ES, Scrimieri F, Winter JM, Hruban RH, Iacobuzio-Donahue C, Kern SE, Blair IA, Tuveson DA

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Caffeine is a natural stimulant found in coffee, tea, chocolate, and many energy drinks

Estradiol has an anorexigenic effect by increasing POMC neuronal activity

In that matched cohort, GLP-1 receptor agonist use was associated with a lower hazard of all-cause mortality, with a reported hazard ratio of 0.09, and a lower hazard of recurrence-free survival events, with a hazard ratio of 0.33 in unadjusted analyses