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GLP-1 receptors in the hypothalamus and brainstem mediate appetite suppression and increased satiety , contributing to reduced food intake and weight loss

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Subsequently, the reaction system was diluted with ethyl acetate (200 mL 3), followed by washing with water (100 mL 3) and saturated sodium chloride solution (100 mL 3)

doi: 10.1016/j.ebiom.2019.11.024 258 LiGLiuYMengFXiaZWuXFangYet al

The interactions of these substituents, both polar and nonpolar, often causes the protein to fold into spherical conformations which gives this class its name

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