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Notably, a similar phenomenon was observed in neurons from patients with MS, characterized by upregulated STING expression and markedly reduced STIM1 expression, suggesting that STIM1-STING-GPX4 axis-mediated ferroptosis is closely associated with neuronal injury in human MS pathology (Woo et al., 2024)
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This is remarkable progress given the historical trends with previous anti-obesity medications used (i.e
But the questions goes mainly towards Scenario 3 from above
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