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I., Bosboom, W

The dose-response relationship is well established

This delayed digestion increases feelings of fullness but makes large, fatty, or complex meals more likely to cause discomfort

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Low GSH, neutrophil infiltration, myeloperoxidase activity and inflammation increase oxidative stress overwhelming the antioxidant defense, and hypochlorous acid mediated GSH oxidation and its attachment to proteins contribute to further GSH deficiency (114)