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Retail and online pharmacies are anticipated to show the fastest growth due to increasing use of technology in healthcare delivery and convenience-seeking patients

In addition, the long-term effects and side effects of GLP-1R agonists need more in-depth studies

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Ideal candidates often include adults who: Experience weight loss resistance despite nutrition and activity changes Have signs of metabolic imbalance or insulin resistance Struggle with appetite dysregulation , frequent cravings, or persistent food noise Have weight gain related to hormonal shifts, stress, or metabolic slowdown Prefer physician-supervised medical weight loss rather than self-directed programs Patients who have not achieved meaningful or sustainable results with diet alone often benefit from addressing the hormonal drivers of hunger, blood sugar instability, and fat storage

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Important observations All five clinical trials that were included in the analysis reported GLP-1 receptor agonist-mediated reduction in substance use disorder, with two trials respectively reporting a significant therapeutic impact of GLP-1 receptor agonist in reducing alcohol use disorder and nicotine use disorder