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The distribution of estimated life-years free of new and recurrent CVD events gained with semaglutide was wide, reflecting variation in absolute benefit gained with semaglutide between patients, with those with higher baseline risk and who were younger at treatment initiation experiencing the greatest absolute benefit. Researchers collected data from the SUSTAIN 6 and PIONEER 6 randomized, double-blind, placebo-controlled trials, both of which evaluated the effects of semaglutide (Wegovy, Novo Nordisk) in people with type 2 diabetes at high risk for CVD
GLP-1 drugs are widely used in this population, yet robust clinical guidance is still evolving
During this time, you can relax while the treatment takes effect
PMID: Summary Keywords Crohns disease, GLP, GLP-1, GLP-2 receptor agonist, IBD - inflammatory bowel disease, ulcerative colitis Citation Lee JJ, Bajgain P and Lightner AL (2026) GLP-1 and GLP-2 as intestinal reparative therapies in inflammatory bowel disease: mechanisms, translation, and clinical opportunity
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