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According to NICE guidance, management primarily involves lifelong thyroid hormone replacement therapy with levothyroxine, which restores normal thyroid hormone levels and alleviates symptoms
But these short-term fixes only scratch the surface with temporary effects
High-dose anabolic androgenic steroids, used at doses far above anything in therapeutic TRT, have been linked to a progressive form of kidney scarring called focal segmental glomerulosclerosis
The answer is yet unclear, but questions like this continue to loom larger
doi: 10.1097/fjc.0000000000000931 115 Mulders-MandersCMBaasMCMolenaarFMSimonA
For example, a clinical trial involving semaglutide reported that participants with a baseline body mass index (BMI) over 35 kg/m lost an average of 15% of their body weight after 68 weeks, while those with lower baseline weights lost less in relative terms
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