Miglustat, sold under the brand name Zavesca as a treatment for Gaucher disease, is the chaperone component of AT-GAA, Amicus Therapeutics investigational therapy for late-onset Pompe disease
Yama/CPP32, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
Retatrutide: The Triple G Drug The most-watched drug in the GLP-1 pipeline is retatrutide (Eli Lilly), which activates three hormone receptors simultaneously: GLP-1, GIP, and glucagon
Semaglutide is a weekly injection, not a daily one
Despite GLP-1s being available for years, there are still so many people holding back from treatment due to stigma, lack of access, or concern over how the medication will fit into their lifestyle, said Laura Steele, group VP of U.S
The STEP trials, which are the major clinical trials of semaglutide for weight management, included detailed psychiatric monitoring