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As of August 2025, we had collected over 27,885 survey respondents who had reported using at least one of Ozempic, Wegovy, compounded semaglutide, Mounjaro, Zepbound or compounded tirzepatide (Extended Data Table 1)

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Indeed, because of their presence in almost every tissue and organ in the body, it is not surprising that fibroblasts are now implicated in multiple and diverse conditions ranging from well-known diseases like cancer, rheumatoid arthritis or fibrosis, to poorly understood ones like fibromyalgia, chronic pain or thyroid eye disease, as we will discuss below ( Figure 1 )

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