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Three different mechanisms, three different pathways, no receptor competition

[1] Renal impairment : Gastrointestinal side effects causing dehydration may precipitate acute kidney injury, particularly in patients with existing renal impairment

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The most practical approach for many protocols involves starting with a 5mg vial for the early escalation phases and switching to a 10mg vial once weekly doses are higher

Koch et al., 2021

They work by mimicking the effects of the natural hormone GLP-1, enhancing insulin secretion, suppressing glucagon release, and promoting satiety or a feeling of fullness