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[4] It occurs naturally in the body but declines with age, dropping from approximately 200 ng/mL at age 20 to around 80 ng/mL by age 60

10.1080/09712119.2010.9707125 92 TkaleviV

This mechanism operates entirely independently of GLP-1 pathways

Both treatments resulted in significant reductions in BMI, hirsutism scores, fasting insulin levels, HOMA index, free testosterone levels, and menstrual irregularity compared to baseline values, demonstrating equal efficacy

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